The present study identifies the components of the medical tourism network and presents a management model for the Tehran metropolis. This research was conducted using a mixed method (qualitative and quantitative). In the qualitative part, using the grounded theory method and conducting semi-structured interviews with experts, causal factors, intervening factors, and consequences of health tourism network management were identified. In the quantitative part, data collected from 310 researcher-made questionnaires among network stakeholders (physicians, managers of medical centers, and health tourism offices) were analyzed using factor analysis and structural equation modeling (SEM). The results showed that coordination among stakeholders, the existence of efficient organizational and managerial platforms, the development of technological infrastructure, and the strengthening of a culture of cooperation have a positive and significant effect on the efficiency and effectiveness of health tourism network management. These findings are consistent with existing research backgrounds and emphasize that in order to improve network management, there is a need to create coordinated structures, develop technological infrastructure, and strengthen a culture of cooperation. The results show that the high therapeutic and specialized capacities in hospitals have provided opportunities for the development of this field. This approach can lead to increased foreign exchange earnings, the creation of sustainable employment, and the strengthening of Tehran's position as a health tourism hub.